Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases

Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases

Oldstone, Michael B. A.; Rosen, Hugh

Springer International Publishing AG

08/2016

184

Mole

Inglês

9783319376035

15 a 20 dias

2993

Descrição não disponível.
The organization of the sphingosine-1-phosphate signaling system.- Structural biology of the S1P1 receptor.- Chemical and genetic tools to explore S1P biology.- S1P control of endothelial integrity.- Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen.- Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule.- Sphingosine-1-phosphate and central nervous system.- RORs in autoimmune disease.
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CNS inflammation;Cytokine storm;Endothelial integrity;Influenza virus infection;Multiple sclerosis;S1P signaling system;infectious diseases