Resistance to Targeted ABC Transporters in Cancer

Role of P-glycoprotein for resistance of tumors to anticancer drugs: From bench to bedside.- Clinical relevance of multidrug-resistance-related proteins (MRPs) for anticancer drug resistance and prognosis.- Role of Breast Cancer Resistance Protein (BCRP, ABCG2) in Cancer Outcomes and Drug Resistance.- A new strategy of ALA-photodynamic cancer therapy: Inhibition of ABC transporter ABCG2.- ABC transporters in cancer stem-like cells.- Radiopharmaceuticals for the imaging of ABC-transporter-mediated multidrug resistance in cancer.- Modulation of P-glycoprotein-mediated multidrug resistance by synthetic and phytochemical small molecules, monoclonal antibodies and therapeutic nucleic acids.- ABC transporter modulatory drugs from marine sources: A new approach to overcome drug resistance in cancer.- The role of ABC multidrug transporters in resistance to targeted anti-cancer kinase inhibitors.- Nanotechnology to combat multidrug resistance in cancer.- Drugs affecting epigenetic modifications of ABC transporters.

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• Oncologia
• Pesquisa médica
• Microbiologia e virologia médicas

P-glycoprotein;anticancer drugs;multidrug resistance;nanotechnology;antibacterial drug resistance