Resistance to Aromatase Inhibitors in Breast Cancer

Resistance to Aromatase Inhibitors in Breast Cancer

Larionov, Alexey

Springer International Publishing AG

10/2016

288

Mole

Inglês

9783319382845

15 a 20 dias

4628

Descrição não disponível.
1 Clinical Use of Aromatase Inhibitors in Breast Cancer: History and Present.-2 Structure, Regulation and Polymorphisms of the Aromatase Gene .-3 Structure, Function and Inhibition of Aromatase.-4 In Vivo Models of AI Resistance.-5 Ineffective inhibition of aromatase: a cause for AI resistance?.-6 Understanding the New Biology of Estrogen-Induced Apoptosis and its Application in Patient Care.-7 Ligand-independent signalling through estrogen receptor pathways in breast cancer.-8 Chromatin and epigenetic determinants of resistance to aromatase inhibitors.-9 Aromatase Inhibitor Resistance via Non-endocrine Signalling Pathways.-10 Prediction of Response to Aromatase Inhibitors in Breast Cancer.-11 Clinical Trials Combining Aromatase Inhibitors with Other Targeted Treatments.-12 Aromatase Inhibitors Beyond Breast Cancer: Endometrium vs Breast Puzzle and Other Issues.
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aromatase protein;breast cancer;estrogen receptor;genetic polymorphism;oestrogens;antibacterial drug resistance