Neuroprotective Therapy for Stroke and Ischemic Disease

Neuroprotective Therapy for Stroke and Ischemic Disease

Zhang, John H.; Lapchak, Paul A.

Springer International Publishing AG

07/2018

795

Mole

Inglês

9783319832722

15 a 20 dias

Descrição não disponível.
Reflections on Neuroprotection Research and the Path Toward Clinical Success.- Systematic review & meta-analysis: important tools in understanding.- Neuroprotection is Technology, not Science.- History of Experimental Stroke Research.- History of Neuroprotection: Trials and Tribulations.- Targeting PSD-95 As a Novel Approach in the Treatment of Stroke.- ATP Sensitive Potassium Channels (KATP) Play a Role in Hypoxic Preconditioning against Neonatal Hypoxic-Ischemic Brain Injury.- Targeting Oxidative Stress in Stroke.- Nitrones, Old Fellows for New Therapies in Ischemic Stroke.- Neuroprotective strategies via modulation of innate immune receptors.- Harnessing the power of the human immune system via multi-omic immune profiling in stroke treatment and recovery.- Polarization of microglia/macrophages in brain ischemia: relevance for stroke therapy.- Endoplasmic Reticulum Stress: An Opportunity for Neuroprotective Strategies after Stroke.- Effects of Neuroprotectants before and after stroke: Statins and Anti-Hypertensives.- Toward Effective Combination Therapy and Pleiotropic Drugs.- TRPM7 Channels as Potential Therapeutic Targets for Stroke Cholinergic Protection in Ischemic Brain Injury.- Remote Ischemic Conditioning: A Highly Translatable Therapy for Acute Stroke.- Hypothermia for Acute Ischemic Stroke.- Modern endovascular treatment of ischemic disease.- Cerebral Microbleeds and Thrombolysis for Acute Ischemic Stroke.- Targeting pericytes and the microcirculation for ischemic stroke therapy.- Thrombolytic and Endovascular Therapies for Acute Ischemic Stroke.- Sonothrombolysis for acute ischemic stroke: a critical appraisal.- Combination Therapy with Thrombolysis.- Oxygen Carriers: Are they enough for cellular support?.- A new paradigm in protecting ischemic brain: preserving the neurovascular unit before reperfusion.- The right rodent for the job: infarct variability between strains and its impact on logistics of experimental animalstudies.- Rabbit Spinal Cord Ischemia Model for the Development of Neuroprotective Treatments.- Stroke Sex Differences: from basic research to clinical trials.- Unpuzzling the co-morbid type 2 diabetes and hypertension-related cognitive dysfunction and stroke.- Sex Specific Factors in Stroke.- Current Imaging Strategies for Patient Selection in Acute Ischemic Stroke Trials
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CNS disorders;thrombolysis;oxidative stress;excitotoxicity;sex-specific