Life Extension
-15%
portes grátis
Life Extension
Lessons from Drosophila
Vaiserman, Alexander M.; Pasyukova, Elena G.; Moskalev, Alexey A.
Springer International Publishing AG
10/2016
353
Mole
Inglês
9783319382104
15 a 20 dias
6166
Descrição não disponível.
Preface.- SECTION I: Genetic regulation of longevity.- Mutations and quantitative genetic variation: lessons from Drosophila.- Modulation of Drosophila lifespan by neuronal genes.- Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45.- Superoxide dismutase over-expression and the mitochondrial unfolded protein response.- Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila.- SECTION II: Drosophila models for aging-associated diseases.- Skeletal muscle homeostasis and aging.- Drosophila models of cardiac disease.- Genetic modulation of cardiac functional aging.- Functional links between circadian clocks, redox state and aging in Drosophila.- Drosophila models in therapeutic drug discovery.- SECTION III: Life-extending treatments.- Phytochemicals with lifespan extension effect in Drosophila.- Life extension in Drosophila by inhibitors of histone deacetylases.- Drosophila healthspan extension using dietary manipulation.- The effect of the artificial atmosphere on the flies' longevity.- Effects of several mild stresses applied in adults on aging and longevity.- Life extension via stage-specific drug interventions in Drosophila.- Index.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Aging;Drosophila;Healthspan;Life extension;Longevity-associated genes
Preface.- SECTION I: Genetic regulation of longevity.- Mutations and quantitative genetic variation: lessons from Drosophila.- Modulation of Drosophila lifespan by neuronal genes.- Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45.- Superoxide dismutase over-expression and the mitochondrial unfolded protein response.- Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila.- SECTION II: Drosophila models for aging-associated diseases.- Skeletal muscle homeostasis and aging.- Drosophila models of cardiac disease.- Genetic modulation of cardiac functional aging.- Functional links between circadian clocks, redox state and aging in Drosophila.- Drosophila models in therapeutic drug discovery.- SECTION III: Life-extending treatments.- Phytochemicals with lifespan extension effect in Drosophila.- Life extension in Drosophila by inhibitors of histone deacetylases.- Drosophila healthspan extension using dietary manipulation.- The effect of the artificial atmosphere on the flies' longevity.- Effects of several mild stresses applied in adults on aging and longevity.- Life extension via stage-specific drug interventions in Drosophila.- Index.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
