Transgenesis and Secondary Metabolism

Part I General Aspects of Transgenesis and Secondary Metabolism: DNA Transfer to Plants by Agrobacterium rhizogenes: A Model for Genetic Communication Between Species and Biospheres.- Secondary Metabolism and the Rationale for Systems Manipulation.- Plant Cell Cultures as Producers of Secondary Metabolites: Podophyllum Lignans as a Model.- Secondary Metabolite Production in Transformed Cultures.- Antimalarial Compound Synthesis from Transgenic Cultures.- Evaluation of Agrobacterium tumefaciens Usefulness for the Transformation of Sage (Salvia Officinalis L.).- Ruta Graveolens: Phytochemistry, Pharmacology and Biotechnology.- Secondary Metabolite Profile of Transgenic Centaury (Centaurium erythraea Rafn.) Plants, Potential Producers of Anticancer Compounds.- Syzygium cumini (L.) Skeels: Cardiometabolic Properties and Potential Tissue Culture-Based Improvement of Secondary Metabolites Production.- Part II Hairy roots and Secondary Metabolism: Secondary Products from Plant Cell Cultures - Early Experiences with Agrobacterium rhizogenes-transformed Hairy Roots.- Secondary Metabolite Production in Transgenic Hairy Root Cultures of Cucurbits.- "Hairy Root" Technology: An Emerging Arena for Heterologous Expression of Biosynthetic Pathway Genes in Medicinal Plants.- Agrobacterium rhizogenes -Mediated Transformation in Medicinal Plants: Genetic Stability in Long Term Culture.- Biotransformation Through Hairy Roots: Perspectives, Outcomes, and Major Challenges.- Part III Metabolic Engineering: Metabolic Engineering of Lignan Biosynthesis Pathways for the Production of Transgenic Plant-Based Foods.- The Elucidation and Metabolic Engineering of Terpenoid Indole Alkaloid Pathway in Catharanthus roseus Hairy Roots.- Pathway Modulation of Medicinal and Aromatic Plants Through Metabolic Engineering Using Agrobacterium tumefaciens.- Metabolic Engineering for Improving the Production of Taxol.- Metabolic Engineering of Phenyl Propanoids in Plants.- Part IV Metabolic Phytochemistry and Functional Analysis: Metabolic Phytochemistry-Based Approaches for Studying Secondary Metabolism Using Transformed Root Culture Systems.- Functional Analysis and the Role of Members of SGT Gene Family of Withania somnifera.- Part V Applications and Future Prospects: Phytochemicals of Nematode-resistant Transgenic Plants?.- Plant Molecular Pharming.- Biotechnological Approaches for Bioremediation: In Vitro Hairy Root Culture.- Genetic Manipulation and Its Contribution to Pharmaceuticals: Past and Future Perspectives.--

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• Ciência da Computação
• Biologia, ciências da vida
• Biotecnologia
• Genética (não médica)
• Química orgânica
• Farmácia / receituário
• Botânica e ciências das plantas
• Bioquímica

Genetic engineering;Plant biotechnology;Medicinal plants;Plant secondary metabolites;Bioactive molecules;Key enzyme encoding genes;Gene over-expression;Metabolic engineering;Functional genomics;Combinatorial biochemistry;Secondary metabolic pathways;Metabolomics