Total Intravenous Anesthesia and Target Controlled Infusions

PART 1. INTRODUCTION/BACKGROUND.- 1. When and How Did It All Begin? A Brief History of Intravenous Anesthesia.- 2. The Development and Regulation of Commercial Devices for Target - Controlled Drug Infusion.- 3. The Memory Labyrinth: systems, processes and boundaries.- 4. Consciousness and Anaesthesia.- 5. Mechanisms of Intravenous Anaesthetic Action.- PART 2. PRINCIPLES OF PHARMACOLOGICAL MODELING.- 6. Basic Pharmacology: Kinetics and Dynamics for Dummies.- 7. Pharmacokinetic-Pharmacodynamic Modelling of Anesthetic Drugs.- 8. Principles of Target Controlled Infusions.- 9. Performance of Target-Controlled Infusion Systems.- 10. How to Select a PK/PD Model.- PART 3. PHARMACOLOGY OF THE INTRAVENOUS ANESTHETIC AGENTS.- 11. Propofol PK-PD.- 12. Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions.- 13. Dexmedetomidine: The Science and Clinical Aspects in Adults and Children.- 14. Clinical Effects and Applications of Ketamine.- 15. Neuromuscular Blocking Drugs: Pharmacology, Physiology and Clinical Aspects.- 16. New and Upcoming Drugs: Intravenous Anesthetic Agents.- 17. Drug Interactions in Anesthesia.- PART 4. PRACTICAL CONDUCT OF SEDATION AND ANESTHESIA18. Pumps Pitfalls and Practicalities.- 19. EEG Monitoring of Depth of Anesthesia.- 20. Monitoring the analgesic component of anesthesia.- 21. Intravenous Drugs for Sedation: Target Controlled, Patient Controlled, and Patient Maintained Delivery.- 22. Pediatric TIVA/TCI: Case Presentations and Discussion.- 23. TCI/TIVA Adult Case Studies.- PART 5. SPECIAL POPULATIONS AND PROCEDURES.- 24. Intravenous Anesthesia in Obese Patients.- 25. Pharmacokinetics and Dynamics on the Pediatric Population.- 26. Clinical Pharmacology of Intravenous Sedation in Children.- 27. Sedation of the Critically Ill Child.- 28. TCI & TIVA for Neurosurgery: Considerations and Techniques.- 29. TCI in Special Patients Groups: The Elderly and Obese.- 30. TIVA for Cardiac Surgery.-31. TIVA/TCI in Veterinary Practice.- PART 6. OUTCOME, EDUCATION, SAFETY, AND THE FUTURE.- 32. Advantages, Disadvantages, and Risks of TIVA/TCI.- 33. Economics of TIVA.- 34. Teaching TCI with Human Patient Simulators.- 35. Closed-Loop or Automated Titration of Intravenous Anesthesia: Background, Science and Clinical Impact.- 36. Health Care Technology, the Human-Machine Interface, and Patient Safety During Intravenous Anesthesia.- 37. Can IV Sedatives Affect Outcome?.- 38. The Benefit and Future of Pharmacogenetics.- 39. Lessons from drug interaction displays.- 40. The Role of Intravenous Agents in Delirium.- 41. Perioperative Cardioprotective Strategies in Noncardiac Surgery.- 42. Opioid Induced Hyperalgesia after Surgery: Clinical Relevance.- 43. Memory, Awareness and Intravenous Anaesthetics.- 44. Awareness and Dreaming During TIVA.- 45. Apoptosis and Neurocognitive Effects of Intravenous Anesthetics.- Epilogues.

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• Cirurgia dos cuidados críticos
• Anestesia

TCI;TIVA;anesthesia;target controlled infusion;total intravenous anesthesia;Trauma Surgery