Systems Biology of Tumor Microenvironment

Systems Biology of Tumor Microenvironment

Quantitative Modeling and Simulations

Rejniak, Katarzyna A.

Springer International Publishing AG

06/2018

249

Mole

Inglês

9783319824802

15 a 20 dias

5696

Descrição não disponível.
Foreword.- Preface.- List of Contributors.- Image Analysis of the Tumor Microenvironment.- Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach.- Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen.- Cell-ECM Interactions in Tumor Invasion.- Circulating Tumor Cells: When Solid tumor Meets Fluid Microenvironment.- Modeling Proteolytically Driven Tumor Lymphangiogenesis.- Positive feedback loops between inflammatory, bone and cancer cells during metastatic niche construction.- Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance.- The Tumor Microenvironment as a Barrier to Cancer Nanotherapy.- Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs.- Optimizing Chemotherapeutic Anti-Cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models.- Progress towards computational 3-D multicellular systems biology.- Index.
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tumor microenvironment;mathematical modeling;quantitative biology;tumor-microenvironment interactions;anti-cancer treatment barriers