Science of Ashwagandha: Preventive and Therapeutic Potentials

PART I Ashwagandha - Phytogenomics and Pharmacology.- Phytochemical Genomics of Ashwagandha.- Phyto-pharmacology of Ashwagandha as An Anti-Diabetic Herb.- Allium cepa Root Chromosomal Aberration Assay: An Application in Assessing Anti-genotoxic Potential of Ashwagandha.- Withania somnifera: From Traditional Use to Evidence Based Medicinal Prominence.- Withanolides: A Prospective Drug for Infectious and Tropical Diseases.- Withania somnifera Extract/Withaferin A As A Prospective Anti-pigmenting Agent.- PART II Ashwagandha for Cancer.- Ashwagandha Bioactives for Cancer Treatment: Experimental Evidence and Their Mechanism(s) of Action.- Scientific Evidence for Anticancer Effects of Withania somnifera And its Primary Bioactive Component Withaferin A.- Withaferin A for Cancer Treatment: Experimental Evidence for its Effect on Telomerase Plus and Minus Cancer Cells.- Withania somnifera Has Potential to Treat Cancer.- The Effects of Withaferin A on Normal And Malignant Immune Cells.- Ashwagandha for Cancer Metastasis: Bioactives and Basics of their Function.- Computational Methods to Understand The Anticancer Mechanism of Withanolides.- PART III Ashwagandha for Brain.- Ashwagandha for Brain Health: Experimental Evidence to its Neuroregenerative Activities.- Cellular and Molecular Targets Underpinning Memory Enhancement by Ashwagandha.- Using Human Neural Stem Cells as A Model to Understand The Science of Ashwagandha.- The Potential Utility of Ashwagandha for Improving Cognitive Dysfunction in Persons with Bipolar or Other Neurocognitive Disorders.- Neuroprotective Potential of Withania somnifera (Ashwagandha) in Neurological Conditions.- Potential Therapeutic Use of Withania somnifera for Treatment of Amyotrophic Lateral Sclerosis.- Neuromodulatory Role of Withania somnifera.- Therapeutic Effects of Ashwagandha in Brain Aging and Clock Disfunction.- PART IV Active Ingredient Enriched Ashwagandha - Biotechnologies.- Biotechnological Approaches in Propagation And Improvement of Withania somnifera (L.) Dunal.- Plant Tissue Culture Based Strategies for Production of Withanolides.- Establishment of Hydroponic Cultivation of Ashwagandha for Active Ingredient Enriched Leaves.

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• Saude pública e medicina preventiva
• Medicina complementar
• Pesquisa médica

Ayurveda;Ashwagandha;Molecular mechanism;Biotechnology;Medicinal use