Organic Cation Transporters
-15%
portes grátis
Organic Cation Transporters
Integration of Physiology, Pathology, and Pharmacology
Gautron, Sophie; Schlatter, Eberhard; Ciarimboli, Giuliano
Springer International Publishing AG
03/2019
264
Mole
Inglês
9783319795348
15 a 20 dias
454
Descrição não disponível.
Introduction to the cellular transport of organic cations.- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism.- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity.- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy.- Physiological and pathological regulation of transporters for organic cations.- Endocrine and metabolic regulation of transporters for organic cations.- Organic cation transporters (OCTs) as modulators of behavior and mood.- Organic cation transporters as modulators of neurodegeneration and neuroprotection.- Translational relevance of animal models for the study of organic cation transporter function.- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
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Cell Membrane;Cytoplasm;Genetics;Molecular biology;Structural biology
Introduction to the cellular transport of organic cations.- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism.- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity.- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy.- Physiological and pathological regulation of transporters for organic cations.- Endocrine and metabolic regulation of transporters for organic cations.- Organic cation transporters (OCTs) as modulators of behavior and mood.- Organic cation transporters as modulators of neurodegeneration and neuroprotection.- Translational relevance of animal models for the study of organic cation transporter function.- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
