Lessons on Caffeine, Cannabis & Co
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Lessons on Caffeine, Cannabis & Co
Plant-derived Drugs and their Interaction with Human Receptors
Boettger, Angelika; Bolle, Cordelia; Vothknecht, Ute; Wolf, Alexander
Springer International Publishing AG
01/2019
217
Mole
Inglês
9783319995458
15 a 20 dias
489
Descrição não disponível.
Introduction: Plant secondary metabolites and their general function in plants.- Historical and current perspective.- Medicinal use.- Recreational use.- General overview over biosynthesis pathways of plant secondary metabolites.- Drugs affecting GPCR: GPCRs in plants and animals.- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin.- Opiate receptors - morphine, salvinorin A.- Cannabinoid receptors - THC.- Muscarinergic acetylcholin receptor - muscarin, atropine.- Adenosine receptor - caffeine.- Drugs affecting ion channels: Ligand and voltage activated channels.- Nicotinic acetylcholin receptor - Nicotine, Curare.- GABAA/C-receptor - Muscimol, thujone.- ionotropic Glycine receptor - Strychnine.- ionotropic Glutamate receptor - ibogtenic acid, kainic acid.- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin.- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants.- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan).- Topoisomerase - camptothecin, etoposide.- G2/M phase arrest, apoptosis - curcubitacin, triptolide.
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Plant secondary metabolites;taxol, seven trans-membrane receptors;ion channels;cell cycle inhibitors;GPCRs;nicotine;caffeine;cannabis;cancer;anti cancer drugs;naturally occuring drugs;cannabinoids;cannabinoid receptor;cannabis mode of action;opioid receptor
Introduction: Plant secondary metabolites and their general function in plants.- Historical and current perspective.- Medicinal use.- Recreational use.- General overview over biosynthesis pathways of plant secondary metabolites.- Drugs affecting GPCR: GPCRs in plants and animals.- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin.- Opiate receptors - morphine, salvinorin A.- Cannabinoid receptors - THC.- Muscarinergic acetylcholin receptor - muscarin, atropine.- Adenosine receptor - caffeine.- Drugs affecting ion channels: Ligand and voltage activated channels.- Nicotinic acetylcholin receptor - Nicotine, Curare.- GABAA/C-receptor - Muscimol, thujone.- ionotropic Glycine receptor - Strychnine.- ionotropic Glutamate receptor - ibogtenic acid, kainic acid.- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin.- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants.- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan).- Topoisomerase - camptothecin, etoposide.- G2/M phase arrest, apoptosis - curcubitacin, triptolide.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
