How to Overcome the Antibiotic Crisis

How to Overcome the Antibiotic Crisis

Facts, Challenges, Technologies and Future Perspectives

Dersch, Petra; Stadler, Marc

Springer International Publishing AG

01/2017

496

Dura

Inglês

9783319492827

15 a 20 dias

8808


ebook

Descrição não disponível.
Tackling threats and future problems of multidrug-resistant bacteria.-Emergence and spread of antimicrobial resistance: recent insights from bacterial population genomics.- Epidemiology of Staphylococcus aureus nasal carriage patterns in the community.- Diagnostics and resistance profiling of bacterial pathogens.- Use of antibiotics and antimicrobial resistance in veterinary medicine as exemplified by the swine pathogen Streptococcus suis.-Antibiotics and the intestinal microbiome: individual responses, resilience of the ecosystem and the susceptibility to infections.- Anti-virulence strategies to target bacterial infections.- Strategies to block bacterial pathogenesis by interference with motility and chemotaxis.- New horizons in the development of novel needle-free immunization strategies to increase vaccination efficacy.- History of antibiotics research.- Actinobacteria and Myxobacteria - Two of the most important bacterial resources for novel antibiotics.- Exploitation of fungal biodiversity for discovery of novel antibiotics.- Strategies for the discovery and development of new antibiotics from natural products: Three Case Studies.- New structural templates for clinically validated and novel targets in antimicrobial drug research and development.- Synthesis of antibiotics.- Antibiotics clinical development and pipeline.- Anti-infectives in drug delivery-overcoming the Gram-negative bacterial cell envelope.
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Antibiotic resistance;Multidrug-resistant bacteria;Antimicrobial resistance;Group B streptococci;Gut microbiota;Multi-resistant bacteria;Anti-virulence strategies;Needle-free immunization strategies;Novel antibiotics;Antimicrobial drug research;infectious diseases