Group-Sequential Clinical Trials with Multiple Co-Objectives
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Group-Sequential Clinical Trials with Multiple Co-Objectives
Asakura, Koko; Evans, Scott R.; Ochiai, Toshimitsu; Hamasaki, Toshimitsu
Springer Verlag, Japan
06/2016
113
Mole
Inglês
9784431558989
15 a 20 dias
454
Descrição não disponível.
1. Introduction.- 2. Early Stopping for Efficacy in Clinical Trials with multiple co-primary endpoints.- 3. Sample size recalculation based on observed effects at interim.- 4. Early stopping for futility in Clinical Trials with multiple co-primary endpoints.- 5. Early stopping for futility or Efficacy in Clinical Trials with multiple co-primary endpoints.- 6. Clinical Trials with multiple primary endpoints.- 7. Group-sequential designs for three-arm noninferiority clinical trials.- 8. Further development: topics not covered in this book.
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Group Sequential Designs;Interim Analysis;Multiple Endpoints;Noninferiority;Sample Size Calculation;Sample Size Recalculation
1. Introduction.- 2. Early Stopping for Efficacy in Clinical Trials with multiple co-primary endpoints.- 3. Sample size recalculation based on observed effects at interim.- 4. Early stopping for futility in Clinical Trials with multiple co-primary endpoints.- 5. Early stopping for futility or Efficacy in Clinical Trials with multiple co-primary endpoints.- 6. Clinical Trials with multiple primary endpoints.- 7. Group-sequential designs for three-arm noninferiority clinical trials.- 8. Further development: topics not covered in this book.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
