Estrogen Receptor and Breast Cancer
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Estrogen Receptor and Breast Cancer
Celebrating the 60th Anniversary of the Discovery of ER
Zhang, Xiaoting
Birkhauser Verlag AG
10/2018
417
Dura
Inglês
9783319993492
15 a 20 dias
811
Descrição não disponível.
1. Introduction: On the discovery of Estrogen Receptor.- 2. Physiological and Pathological Roles of Estrogen Receptor.- 3. Estrogen Receptor Cofactors.- 4. ER-Mediated Gene Transcription.- 5. ER Transcriptome .- 6. Estrogen Receptor Regulation of Non-Coding RNAs in Breast Cancer .- 7. First Targeted Therapy --- History of Tamoxifen.- 8. Selective Estrogen Receptor Modulators (SERMs).- 9. New Estrogen Receptor Drugs.- 10. Endocrine Therapy in Clinical Practice.- 11. Structural Insights into ER and Anti-Estrogen Therapies.- 12. Molecular Mechanisms of Endocrine Resistance.- 13. Estrogen Receptor Mutants in Breast Cancer.- 14. Estrogen Receptor Beta and Isoforms in Breast Cancer.- 15. Xenoestrogens, Phytoestrogens and Breast Cancer.- 16. Emerging Approaches to Overcome Endocrine Resistance.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
estrogen receptor;breast cancer;targeted therapies against ER pathways;Tamoxifen;molecular functions of ER
1. Introduction: On the discovery of Estrogen Receptor.- 2. Physiological and Pathological Roles of Estrogen Receptor.- 3. Estrogen Receptor Cofactors.- 4. ER-Mediated Gene Transcription.- 5. ER Transcriptome .- 6. Estrogen Receptor Regulation of Non-Coding RNAs in Breast Cancer .- 7. First Targeted Therapy --- History of Tamoxifen.- 8. Selective Estrogen Receptor Modulators (SERMs).- 9. New Estrogen Receptor Drugs.- 10. Endocrine Therapy in Clinical Practice.- 11. Structural Insights into ER and Anti-Estrogen Therapies.- 12. Molecular Mechanisms of Endocrine Resistance.- 13. Estrogen Receptor Mutants in Breast Cancer.- 14. Estrogen Receptor Beta and Isoforms in Breast Cancer.- 15. Xenoestrogens, Phytoestrogens and Breast Cancer.- 16. Emerging Approaches to Overcome Endocrine Resistance.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
