Essentials of Clinical Research

Essentials of Clinical Research

Glasser, Stephen P.

Springer International Publishing AG

08/2016

461

Mole

Inglês

9783319376837

15 a 20 dias

7022

Descrição não disponível.
Preface.- The Beginning, Historical Aspects of Clinical Research, Clinical Research: Definitions, "Anatomy and Physiology," and the Quest for "Universal Truth".- Introduction to Clinical Research Concepts, Essential Characteristics of Clinical Research, Overview of Clinical Research Study Designs.- A Focus on Clinical Trials.- Alternative Interventional Study Designs.- Phase 4 (Postmarketing) Research.- The Role of the USA Food and Drug Administration in Clinical Research.- The Placebo and Nocebo Effect.- Recruitment and Retention in Clinical Research.- Data Safety and Monitoring Boards (DSMBs).- Meta-analysis, Evidence Based Medicine, and Clinical Guidelines.- Research Methods for Genetic Studies.- Research Methods for Pharmacoepidemiology Studies.- Implementation Research: Beyond the Traditional Randomized Controlled Trial.- Research Methodology for Studies of Diagnostic Tests.- Statistical Power & Sample Size: Some Fundamentals For Clinician Researchers.- Association,Cause, and Correlation.- Bias, Confounding, and Effect Modification (Interaction).- It's All About Uncertainty.- Grant and Manuscript Writing.- The Media and Clinical Research.- Mentoring and the Mentee.- Presentation Skills: How to Present Research Results.
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clinical research;clinical trials;metaanalysis;new drug development;pharmacoepidemiology;placebo and nocebo