Development of Mirror-Image VHHs with Less Immunogenicity

Development of Mirror-Image VHHs with Less Immunogenicity

Aoki, Keisuke

Springer Nature Switzerland AG

02/2025

116

Dura

9789819613007

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Chapter 1.Introduction.- Chapter 2.Chemical Synthesis of Mirror-Image VHHs and Evaluation of Their Immunogenicity.- Chapter 3.Identification of a Mirror-Image VHH against Vascular Endothelial Growth Factor.- Chapter 4.Synthetic Study of Full-Length Hepatitis B Virus Core Protein and Its Capsid Assembly.- Chapter 5.Chemical Synthesis of Interleukin-6 for Mirror-Image VHH Discovery.- Chapter 6.Conclusions.
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Chemical protein synthesis;Mirror-image protein;Single-domain antibody;VHH;Immunogenicity;Phage display