Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Pathobiology, B Cell Receptors, Novel Mutations, Clonal Evolution

Kaur, Prabhjot

Birkhauser

06/2019

135

Mole

Inglês

9783319889672

15 a 20 dias

This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for pathologists and clinical hematologists/oncologists with an interest in chronic lymphocytic leukemia.
Definition, Epidemiology, Monoclonal B cell lymphocytosis, Morphology , Immunophenotype, Transformation, Gene expression profiling.- Chromosomal aberrations in CLL :Karyotype and FISH.- B cell receptors (BCRs).- Novel mutations in CLL.- Clonal evolution and the Driver/Passenger Mutation Model in CLL.- Prognosis and predictive factors - Hierarchal classification.- MiRNAs.
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