Chromatin Regulation of Early Embryonic Lineage Specification

Chromatin Regulation of Early Embryonic Lineage Specification

Knott, Jason; Latham, Keith

Springer International Publishing AG

12/2017

78

Mole

Inglês

9783319631868

15 a 20 dias


Versão ebook 89,99 €

Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE).
CHD1 controls cell lineage specification through zygotic genome activation.- Chromatin remodelling proteins and cell fate decisions in mammalian preimplantation development.- Transcriptional regulation and genes involved in first lineage specification during preimplantation development.- ROCK and RHO playlist for preimplantation development: Streaming to HIPPO pathway and apicobasal polarity in the first cell differentiation.- XEN and the art of stem cell maintenance - molecular mechanisms maintaining cell fate and self-renewal in extraembryonic endoderm stem (XEN) cell lines.
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