Capillary Electrophoresis-Mass Spectrometry

Capillary Electrophoresis-Mass Spectrometry

Therapeutic Protein Characterization

Xia, James Q.; Zhang, Lichao

Springer International Publishing AG

06/2018

74

Mole

Inglês

9783319834757

15 a 20 dias

1416

Descrição não disponível.
Introduction to Capillary Electrophoresis-Mass Spectrometry.- Coated Capillaries for CE-MS of Therapeutic Protein.- Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis-Mass Spectrometry.- Separation and Characterization of Proteins and Peptides in Biological Fluids using CE-MS.- Host Cell Protein Analysis using CE-MS.- Antibody PTM Analysis using CE-MS.- Characterization of Intact Therapeutic Proteins and Protein Subunits using CE-MS Platform.
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ADCs;CE-MS;Monoclonal antibody;PK study of biologics analysis;PTMs;Protein glycosylation profiling;cIEF-MS technology;capillary electrophoresis-mass spectrometry;characterization of antibody-drug conjugates;combining LC-MS with CE-MS workflow;mass spectrometry;peptide mapping of monoclonal antibody;posttranslational modifications;protein sequence coverage;recombinant therapeutic proteins