Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

Preface.- I. The Biology of Cancer Stem Cells.- Cancer Stem Cells: A Quick Walk through the Concepts.- Cytokine Networks and Cancer Stem Cells.- Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression.- Non-coding RNAs in Cancer and Cancer Stem Cells. Self-renewal Pathways in Mammary Stem Cells and Carcinogenesis II. Cancer Stem Cells in Human Malignancies.- Breast Cancer Stem Cells.- Lung Cancer Stem Cells.- Colorectal Cancer Stem Cells.- Pancreatic Cancer Stem Cells.- Glioblastoma Cancer Stem Cells.- Head and Neck Cancer Stem.- Leukemic and Lymphoid Stem Cells.- Leukemic Stem Cells in Acute Lymphoblastic Leukemia.- III. Novel Approaches for Targeting Cancer Stem Cells.- Targeting Key Stemness-Related Pathways in Human Cancers.- Targeting Cancer Stem Cells and the Tumor Microenvironment.- Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance.- Cancer Stem Cells and Tumor Radioresistance.- Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies. Index.

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• Pesquisa médica
• Genética médica
• Oncologia
• Microbiologia e virologia médicas

Cancer stem cells;Chemoresistance;Stem cell pathways;Therapy;Translational studies;antibacterial drug resistance