Cancer II

Cancer II

Waring, Michael J.

Springer International Publishing AG

11/2018

475

Dura

Inglês

9783319759241

15 a 20 dias


Versão ebook 199,00 €

This book reviews recent breakthroughs in anti-cancer drug discovery. Each chapter provides an overview of the underlying biology and then emphasises the medicinal chemistry strategies and tactics that led to the most significant drugs and drug candidates.
Progress in the Discovery of BCR-ABL Kinase Inhibitors for the Treatment of Leukemia.- Small Molecule Inhibitors of the Epidermal Growth Factor Receptor.- Small-Molecule Inhibitors of Bruton's Tyrosine Kinase.- Inhibitors of Vascular Endothelial Growth Factor Receptor.- Inhibitors of the Fibroblast Growth Factor Receptor.- Modulation of the DNA-Damage Response by Inhibitors of the Phosphatidylinositol 3-Kinase Related Kinase (PIKK) Family.- Epigenetic Modulators.- Antibody-Drug Conjugates.- Isoform Selective PI3K Inhibitors for Treating Cancer.- Inhibitors of the Kynurenine Pathway.- Protein-Protein Interaction Inhibitors.- Small Molecule Inhibitors of ALK.
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