Biological Basis of Alcohol-Induced Cancer

Biological Basis of Alcohol-Induced Cancer

Hoek, Jan B.; Seitz, Helmut K.; Vasiliou, Vasilis; Zakhari, Samir

Springer International Publishing AG

09/2016

436

Mole

Inglês

9783319378558

15 a 20 dias

7611

Descrição não disponível.
Introduction.- Alcohol and breast cancer: Reconciling epidemiological and molecular data.- Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking.- Alcohol and Cancer: an Overview With special Emphasis on the Role of Acetaldehyde and Cytochrome P-4502E1.- Implications of acetaldehyde-derived DNA adducts for understanding alcohol related carcinogenesis.- The role of iron in alcohol-mediated hepatocarcinogenesis.- Alcoholic Cirrhosis and Hepatocellular Carcinoma.- TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis.- Synergistic Toxic Interactions Between CYP2E1, LPS/TNF? and JNK/p38 MAP Kinase and their Implications in Alcohol-induced Liver Injury.- Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma.- Alcohol consumption, Wnt/b-catenin signaling and hepatocarcinogensis.- Alcohol and HCV: Implications for Liver Cancer.- Application ofMass Spectrometry-based Metabolomics in Identification of Early Noninvasive Biomarkers of Alcohol-Induced Liver Disease Using Mouse Model.- Alcohol Metabolism by Oral Streptococci and Interaction with Human Papillomavirus Leads to Malignant Transformation of Oral Keratinocytes.- Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers.- Acetaldehyde and Retinaldehyde-Metabolizing Enzymes in Colon and Pancreatic cancers.- Alcohol, Carcinoembryonic Antigen Processing and Colorectal Liver Metastases.- Alcohol Consumption and Antitumor Immunity: Dynamic Changes from Activation to Accelerated Deterioration of the Immune System.- A Perspective on Chemoprevention by Resveratrol in Head and Neck Squamous Cell Carcinoma.- The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.- The effect of alcohol on sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC).- Transgenic Mouse Models for Alcohol Metabolism, Toxicity and Cancer.- Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate gland.- Fetal Alcohol Exposure and Mammary Tumorigenesis in Offspring: Role of the Estrogen and Insulin-like Growth Factor Systems.
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acetaldehyde;cirrhosis;hepatocarcinogenesis;liver cancer