Alagille Syndrome

Alagille Syndrome

Pathogenesis and Clinical Management

Kamath, Binita M.; Loomes, Kathleen M.

Springer International Publishing AG

10/2018

198

Dura

Inglês

9783319945705

15 a 20 dias

561


ebook

Descrição não disponível.
The Alagille Syndrome: Overview and Introduction.- Bile Duct Development and the Notch Signaling Pathway.- Genetics of Alagille Syndrome.- Liver Disease in Alagille Syndrome.- Transplant Considerations in Alagille Syndrome.- Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille Syndrome.- Vascular Manifestations in Alagille Syndrome.- The Renal Sequelae of Alagille Syndrome as a Product of Altered Notch Signaling During Kidney Development.- Skeletal Involvement in Alagille Syndrome.- Immune Dysregulation in Alagille Syndrome: A Feature of the Evolving Phenotype.- Health-Related Quality of Life and Neurocognition in Alagille Syndrome.- Future Therapeutic Approaches for Alagille Syndrome.
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bile duct development;notch signaling pathway;complex biliary diseases;transplant;immune system;hepatology