5-HT2A Receptors in the Central Nervous System

Pharmacological analysis in favour of a physiological role for the constitutive activity of 5-HT2A receptors in learning.- ?Arrestins: Ligand-directed regulators of 5-HT2A receptor trafficking and signaling events.- 5-HT2A receptor heterodimerization Brain distribution.- PET imaging of the 5-HT2A receptor system: A tool to study the receptor's in vivo brain function.- Serotonergic receptor 5-HT2A in the cardiosympathovagal system.- Crosstalk between 5-HT2A and mGlu2 receptors: Implications in schizophrenia and its treatment.- Schizophrenia.- Role of Serotonin-2A Receptors in Pathophysiology and Treatment of Depression.- Brain circuits regulated by the 5-HT2A receptor: behavioural consequences on anxiety and fear memory.- 5-HT2A/2B/2C Receptors, Memory and Therapeutic Targets.- 5-HT2A receptors in the basal ganglia.- The involvement of 5-HT2A receptor in the regulation of sleep and wakefulness, and the potential therapeutic use of selective 5-HT2A receptor antagonists and inverse agonists for the treatment of an insomnia disorder.- 5-HT2A receptors and Pain.- 5-HT2A receptors in eating disorders.- Role of Serotonin2A (5-HT2A) Receptors in Epilepsy.- 5-HT2A receptors and BDNF regulation: Implications for Psychopathology.

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• Neurociências

5HT2A receptors;G-protein coupled receptors;neuropsychiatric disorders;pharmacology;physiology;trafficking;brain;imaging;schizophrenia;Pathophysiology;eating disorders;epilepsy